Character Name : Osmosis Jones (voice)

Original Name : Chris Rock

Gender : Male

Character Name : Thrax (voice)

Original Name : Laurence Fishburne

Gender : Male

Character Name : Drix (voice)

Original Name : David Hyde Pierce

Gender : Male

Character Name : Leah (voice)

Original Name : Brandy Norwood

Gender : Female

Character Name : Frank Detorre

Original Name : Bill Murray

Gender : Male

Character Name : Mrs. Boyd

Original Name : Molly Shannon

Gender : Female

Character Name : Mayor Phlegmming (voice)

Original Name : William Shatner

Gender : Male

Character Name : Tom Colonic (voice)

Original Name : Ron Howard

Gender : Male

Character Name : (voice)

Original Name : Sherry Lynn

Gender : Female

Character Name : Additional Character Voice (voice)

Original Name : Mickie McGowan

Gender : Female

Character Name : Bob

Original Name : Chris Elliott

Gender : Male

Character Name : Shane Detorre

Original Name : Elena Franklin

Gender : Female

Character Name : Kidney Rock

Original Name : Kid Rock

Gender : Male

Character Name : Kidney Rock (voice)

Original Name : Uncle Kracker

Gender : Male

Character Name : Additional Character Voices (voice)

Original Name : Carlos Alazraqui

Gender : Male

Character Name : Additional Character Voices (voice)

Original Name : Rodger Bumpass

Gender : Male

Character Name : Additional Character Voices (voice)

Original Name : Richard Steven Horvitz

Gender : Male

Character Name : Additional Character Voices (voice)

Original Name : Danny Mann

Gender : Male

Character Name : Additional Character Voices (voice)

Original Name : Mickie McGowan

Gender : Female

Character Name : Additional Character Voices (voice)

Original Name : Jonathan Adams

Gender : Male