Character Name : 'Weird Al' Yankovic

Original Name : Daniel Radcliffe

Gender : Male

Character Name : Madonna

Original Name : Evan Rachel Wood

Gender : Female

Character Name : Dr. Demento

Original Name : Rainn Wilson

Gender : Male

Character Name : Nick Yankovic

Original Name : Toby Huss

Gender : Male

Character Name : Jim

Original Name : Jack Lancaster

Gender : Male

Character Name : Steve

Original Name : Spencer Treat Clark

Gender : Male

Character Name : Bermuda

Original Name : Tommy O'Brien

Gender : Male

Character Name : Pablo Escobar

Original Name : Arturo Castro

Gender : Male

Character Name : Mary Yankovic

Original Name : Julianne Nicholson

Gender : Female

Character Name : Grizzled Narrator (voice)

Original Name : Diedrich Bader

Gender : Male

Character Name : Doctor

Original Name : Lin-Manuel Miranda

Gender : Male

Character Name : Young Al

Original Name : Richard Aaron Anderson

Gender : Male

Character Name : Salesman

Original Name : Thomas Lennon

Gender : Male

Character Name : Teenage Al

Original Name : David Bloom

Gender : Male

Character Name : Kip

Original Name : Keanush Tafreshi

Gender : Male

Character Name : Robbie

Original Name : Andrew Steven Hernandez

Gender : Male

Character Name : Hipster Teen

Original Name : Paloma Esparza Rabinov

Gender : Female

Character Name : Police Officer

Original Name : Scott Aukerman

Gender : Male

Character Name : Johnny Barf

Original Name : Johnny Pemberton

Gender : Male

Character Name : Jonah Barf

Original Name : Jonah Ray Rodrigues

Gender : Male

Character Name : Jeremy Barf

Original Name : Jeremy Bolm

Gender : Male

Character Name : Captain Buffoon (voice)

Original Name : Eric Appel

Gender : Male

Character Name : Tony Scotti

Original Name : 'Weird Al' Yankovic

Gender : Male

Character Name : Ben Scotti

Original Name : Will Forte

Gender : Male

Character Name : Heckler

Original Name : Patton Oswalt

Gender : Male

Character Name : Sleazy MC

Original Name : Michael McKean

Gender : Male

Character Name : Mama Bear

Original Name : Dot-Marie Jones

Gender : Female

Character Name : Bartender

Original Name : Dean Sharpe

Gender : Male

Character Name : Pee-Wee Herman

Original Name : Jorma Taccone

Gender : Male

Character Name : Tiny Tim

Original Name : Demetri Martin

Gender : Male

Character Name : Gallagher

Original Name : Paul F. Tompkins

Gender : Male

Character Name : Alice Cooper

Original Name : Akiva Schaffer

Gender : Male

Character Name : Andy Warhol

Original Name : Conan O'Brien

Gender : Male

Character Name : Salvador Dali

Original Name : Emo Philips

Gender : Male

Character Name : Divine

Original Name : Nina West

Gender : Male

Character Name : Wolfman Jack

Original Name : Jack Black

Gender : Male

Character Name : John Deacon

Original Name : David Dastmalchian

Gender : Male

Character Name : Security Guard

Original Name : Anthony N.

Gender : Male

Character Name : Oprah Winfrey

Original Name : Quinta Brunson

Gender : Female

Character Name : Connie Chung

Original Name : Julie Chang

Gender : Male

Character Name : Waiter

Original Name : Josh Groban

Gender : Male

Character Name : Radio DJ (voice)

Original Name : Seth Green

Gender : Male

Character Name : Cone-Bra Dancer #1

Original Name : Constantine Rousouli

Gender : Male

Character Name : Cone-Bra Dancer #2

Original Name : James Brown III

Gender : Male

Character Name : Terrorist Diner Patron

Original Name : Rocky Abou-Sakher

Gender : Male

Character Name : Kidnapper

Original Name : Chris Ryan

Gender : Male

Character Name : Guard #1

Original Name : Mike Escamilla

Gender : Male

Character Name : Guard #2

Original Name : Chad Guerrero

Gender : Male

Character Name : Mariachi Band Member #1

Original Name : Cesar Ramirez

Gender : Male

Character Name : Mariachi Band Member #2

Original Name : Omar Estrada

Gender : Male

Character Name : Mariachi Band Member #3

Original Name : Cesar Chavira

Gender : Male

Character Name : Floor Manager

Original Name : Jimmy Walker Jr.

Gender : Male

Character Name : Diana Ross

Original Name : Trenyce

Gender : Male

Character Name : Hulk Hogan

Original Name : James Preston Rogers

Gender : Male

Character Name : Sicario

Original Name : William Guirola

Gender : Male

Character Name : Elton John (uncredited)

Original Name : Paul Riley Fox

Gender : Male

Character Name : David Bowie (uncredited)

Original Name : Gordon Tarpley

Gender : Male

Character Name : Elvira, Mistress of the Dark (uncredited)

Original Name : Lisa Margaroli

Gender : Male

Character Name : Kate Pierson (uncredited)

Original Name : Erin O'Shea

Gender : Male