Character Name : Dr. Slavkin O'Hara

Original Name : Michael Sheen

Gender : Male

Character Name : Patricia Herman

Original Name : Toni Collette

Gender : Female

Character Name : Henry James Herman

Original Name : Jason Spevack

Gender : Male

Character Name : Audrey O'Hara

Original Name : Samantha Weinstein

Gender : Male

Character Name : Kindergarten Teacher

Original Name : Melyssa Ade

Gender : Female

Character Name : Oprah

Original Name : Oprah Winfrey

Gender : Female

Character Name : Stan Herman

Original Name : Frank Moore

Gender : Male

Character Name : Dr. Gunther Flowers

Original Name : Paul Braunstein

Gender : Male

Character Name : Young Patricia Herman

Original Name : Hannah Brigden

Gender : Male

Character Name : Mother Herman

Original Name : Sarah Orenstein

Gender : Female

Character Name : Young Billy Herman

Original Name : Jamie Johnston

Gender : Male

Character Name : Tim Herman

Original Name : Mark MacDonald

Gender : Male

Character Name : Tom Herman

Original Name : Mickey MacDonald

Gender : Male

Character Name : Jimmy Herman

Original Name : Cameron Kennedy

Gender : Male

Character Name : Alice O'Hara

Original Name : Kate Hewlett

Gender : Female

Character Name : Delivery Room Doctor

Original Name : Kevin Hare

Gender : Male

Character Name : Brian the Bully

Original Name : Austin Macdonald

Gender : Male

Character Name : Miss Abda

Original Name : Mishu Vellani

Gender : Female

Character Name : Malcom's Dad / Nurse Stewart

Original Name : Aaron Abrams

Gender : Male