Character Name : James Isaac 'Jimmy' Neutron (voice)

Original Name : Debi Derryberry

Gender : Female

Character Name : Jet Fusion (voice)

Original Name : Christian Slater

Gender : Male

Character Name : Beautiful Gorgeous (voice)

Original Name : Wendie Malick

Gender : Female

Character Name : Commander Baker (voice)

Original Name : Michael Clarke Duncan

Gender : Male

Character Name : Professor Calamitous (voice)

Original Name : Tim Curry

Gender : Male

Character Name : Professor Crank (voice)

Original Name : Dan Castellaneta

Gender : Male

Character Name : Goddard (voice)

Original Name : Frank Welker

Gender : Male

Character Name : Carl Wheezer / Monk / Voice / Clam (voice)

Original Name : Rob Paulsen

Gender : Male

Character Name : Judy Neutron / Ms. Jingle Bells / Female Monk (voice)

Original Name : Megan Cavanagh

Gender : Female

Character Name : Hugh Neutron (voice)

Original Name : Mark DeCarlo

Gender : Male

Character Name : Sheen Estevez (voice)

Original Name : Jeffrey Garcia

Gender : Male

Character Name : Ms. Fowl (voice)

Original Name : Andrea Martin

Gender : Female

Character Name : Cindy Vortex / Tina Sue (voice)

Original Name : Carolyn Lawrence

Gender : Female

Character Name : Libby Fallfax / Ike (voice)

Original Name : Crystal Scales

Gender : Female

Character Name : Betty Quinlan (voice)

Original Name : Kath Soucie

Gender : Female

Character Name : Narrator / Head Monk

Original Name : Corey Burton

Gender : Male

Character Name : Chief (voice)

Original Name : Ving Rhames

Gender : Male